- 10% of cases are discovered incidentally, when the patient is undergoing diagnostics for other conditions.
- Pheochromocytomas can be a component of certain genetic syndromes.
- It is possible to have pheochromocytomas with no family history of them.
- Pheochromocytomas are often associated with von Hippel-Lindau syndrome and neurofibromatosis.
- The incidence of pheochromocytoma is 2 to 8 per million persons per year.
Pheochromocytoma is present in 0.1% to 1% of patients with hypertension,and it is present in approximately 5% of patients with incidentally discovered adrenal masses. The peak incidence occurs in the third to fifth decades of life; the average age at diagnosis is 24.9 years in hereditary cases and 43.9 years in sporadic cases. The incidence is equal between males and females. Source